Resolving Spectra Overlapping Based on Net Analyte Signal for Simultaneous Spectrophotometric Determination of Fluoxetine and Sertraline

Document Type : Research Paper

Authors

1 Department of Chemistry, Faculty of Chemistry, Azad University, North Tehran Branch, Tehran, Iran

2 Department of Biophysics, Faculty bof Biological Sciences, Tarbiat Modares University, Tehran, Iran

Abstract

The net analyte signal standard addition method was used for simultaneous spectrophotometric determination of sertraline and fluoxetine in pharmaceutical preparations. The method combines the advantages of the standard addition method with the net analyte signal concept to enable the extraction of information about an analyte from the spectra of multi-component mixtures. This method uses full spectrum realization and does not require calibration and prediction steps. Determination requires only a few measurements. The limit of detection for fluoxetine was 0.31 µg ml-1 and for sertraline was 0.20 µg ml-1. The root mean square error for fluoxetine was 0.45 and for sertraline was 0.39.

Keywords

References

[1] H. Martens, T. Naes, Multivariate Calibration, John Wiley, New York, 1992.
[2] P.D. Wentzell, L.V. Montoto, Chemometr. Intell. Lab. Syst. 65 (2003) 257.
[3] M. Barker, W. Rayens, J. Chemometrics 17 (2003) 166.
[4] S. Ren, L. Gao, Talanta 50 (2000) 1163.
[5] A. Lorber, Anal. Chem. 58 (1986) 1167.
[6] N.M. Faber, Anal. Chem. 71 (1999) 557.
[7] R. Boqu´e, J. Ferr´e, N.M. Faber, F.X. Rius, Anal. Chim. Acta 451 (2002) 313.
[8] N.M. Faber, J. Ferre, R. Boque, J.H. Kalivas, Trends Anal. Chem. (2003) 22.
[9] N.M. Faber, Anal. Chem. 70 (1998) 5108.
[10] A. Lorber, K. Faber, B.R. Kowalski, Anal. Chem. 69 (1997) 1620.
[11] K. Faber, A. Lorber, B.R. Kowalski, J. Chemometr. 11 (1997) 419.
[12] J.T. Olesberg, M.A. Arnold, B. Shih-Yao, B. Shih-Yao Hu, J.M. Wiencek, Anal. Chem. 72 (2000) 4985.
[13] L. Xu, I. Schechter, Anal. Chem. 69 (1997) 3722.
[14] H.C. Goicoechea, A.C. Olivieri, Chemometr. Intell. Lab. Syst. 56 (2001) 73.
[15] N.R. Marsili, M.S. Sobrero, H.C. Goicoechea, Anal. Bioanal. Chem. 376 (2003) 126.
[16] A.E. Mansilla, I.D. Meras, M.J.R. Gomez, A. Munoz de la Pena, F. Salinas, Talanta 58 (2002) 255.
[17] G.V. Truyols, J.R. Torres-Lapasio, M.C. Garc´ya-Alvarez-Coque, J. Chromatogr. A 991 (2003) 47.
[18] A. Munz de la Pena, A.E. Mansilla, M.I.A.A. Valenzuela, H.C. Goicoechea, A.C. Olivieri, Anal. Chim. Acta 463 (2002) 75.
[19] A. Lorber, Anal. Chem. 69 (1997) 1620.
[20] J.H. Jiang, R.J. Berry, H.W. Siesler, Y. Ozaki, Anal. Chem. 74 (2002) 3555.
[21] C.H. Spiegelman, M.J. McShane, M.J. Goetz, M. Motamedi, Q.L. Yue, G.L. Cote, Anal. Chem. 70 (1998) 35.
[22] H.C. Goicoechea, A.C. Olivieri, J. Chem. Inf. Comput. Sci. 42 (2002) 1146.
[23] J.H. Kalivas, N. Roberts, J.M. Sutter, Anal. Chem. 61 (1989) 2024.
[24] R. Leardi, J. Chemometr. 8 (1994) 65.
[25] V. Centner, D.L. Massart, O.E. deNoord, S. Jong, B.M. Vandeginste, C. Sterna, Anal. Chem. 68 (1996) 3851.
[26] B.K. Alsberg, A.M. Woodward, M.K. Winson, J.J. Rowl, D.B. Kell, Anal. Chim. Acta 368 (1998) 29.
[27] M.C.U. Araujo, T.C.B. Saldanha, R.K.H. Galvao, T. Yoneyama, H.C. Chame, V. Visani, Chemometr. Intell. Lab. Syst. 57 (2001) 65.
[28] H.C. Goicoechea, A.C. Olivieri, Analyst 124 (1999) 725.
[29] S.M. Sampson, Mayo Clin. Proc. 76 (2001) 739.
[30] Moffat AC, Osselton MD, Widdop B. Clarke’s analysis of drugs and poisons. London: Pharmaceutical Press; 2004.
[31] http://medicine complete.com// Fluoxetine Clark’s analysis of drug and poison.htm
[32] D. Murdoch, D. McTavish, Drugs 44 (1992) 604.
[33] J.F. Nash, R.J. Bopp, R.H. Carmichael, K.Z. Farid, L. Lemberger, Clin. Chem. 28 (1982) 2100.
[34] S.H.Y. Wong, S.S. Dellafera, R. Fernandes, H. Kranzler, J. Chromatogr. 499 (1990) 601.
[35] J.G. Flood, P.R. Puopolo, Clin. Chem. 37 (1991) 1304.
[36] P. Thomare, K. Wang, V. van der Meerch-Mougeot, B. Diquet, J. Chromatogr. 121 (1992) 217.
[37] A. El-Yazigi, D.A. Ruines, Ther. Drug Monit. 15 (1993) 305.
[38] J.H. Nichols, J.R. Charlson, G.M. Lawson, Clin. Chem. 40 (1994) 1312.
[39] D.D. Writh, B.A. Olsen, D.K. Hallenbeck, M.G. Lake, S.M. Gregg, F.M. Perry, Chromatographia 46 (1997) 511.
[40] G. Aymard, P. Lidi, Y.T. Pham, B. Diquet, J. Chromatogr. Biomed. Appl. 700 (1997) 183.
[41] V. Dixit, H. Nguyen, V.M. Dixit, J. Chromatogr. Biomed. Appl. 101 (1991) 379.
[42] G.A. Torok-Both, G.B. Baker, R.T. Coutts, K.F. Mckenna, L.J. Aspeslet, J. Chromatogr. Biomed. Appl. 117 (1992) 99.
[43] R.T. Sane, A.B. Jani, J.K. Ghodge, A.J. Vaidya, S.S. Kotwal, Indian Drugs 29 (1992) 237.
[44] S. Raghuveer, A.B. Avadhanulu, A.R.R. Pantulu, Indian Drugs 30 (1993) 83.
[45] B. Levine, A.J. Jenkins, J.E. Smialek, J. Anal. Toxicol. 18 (1994) 272.
[46] D. Rogowsky, M. Marr, G. Long, C. Moore, J. Chromatogr. Biomed. Appl. 655 (1994) 138.
[47] B.K. Logan, P.N. Friel, G.A. Case, J. Anal. Toxicol. 18 (1994) 139.
[48] H.G. Fouda, R.A. Ronfeld, D.J. Weidler, J. Chromatogr. Biomed. Appl. 61 (1987) 197.
[49] L.M. Tremaine, E.A. Joerg, J. Chromatogr. Biomed. Appl. 88 (1989) 423.
[50] R.N. Gupta, S.A. Dziurdzy, Clin. Chem. 40 (1994) 498.
[51] H.L. Wiener, H.K. Kramer, M.E.A. Reith, J. Chromatogr. Biomed. Appl. 92 (1990) 467.
[52] J. Patel, E.P. Spencer, R.J. Flangan, Biomed. Chromatogr. 10 (1996) 351.
Theory
[53] A. Lorber, Anal. Chem. 58 (1988) 1167–1172.
[54] A. Lorber, K. Faber, B.R. Kowalski, Anal. Chem. 69 (1997) 1620–1626.
[55] N.M. Faber, Anal. Chem. 70 (1998) 5108.
[56] M.A. Cantarelli, R.G. Pellerano, E.J. Marchevsky, J.M. Camina, Anal. Sci. 27 (2011) 73-78.

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